Cow is a print featuring a close-up image of a cow in vivid pink and yellow hues. Warhol’s dealer described it as "blazingly bright," underscoring the work as a vivid example of Warhol’s continually evolving subject matter.

Though initially unconventional, Warhol’s Cow draws from a rich tradition of classical imagery, where cows have appeared in Renaissance and academic art. Warhol’s version offers a contemporary twist with a psychedelic colour palette that embodies the spirit of the 1960s and 1970s. Just as he elevated glamorous figures like Marilyn Monroe and Elizabeth Taylor to high art with his screenprints, Warhol gives the ordinary farm animal a similar prominence. This approach adds a playful and whimsical dimension to the portrait, challenging the typical association of Warhol with celebrity worship.